Academic qualifications:
2000 - 2004: Degree in Biology, University of Athens, School of Sciences, Department of Biology
2004 - 2010: Degree in Medicine, University of Athens, Medical School
2005 - 2010: PhD University of Ioannina, Medical School, Department of Pathology in collaboration with Department of Genetics, Saint Savas Hospital, Athens
Foreign languages and computer use:
English: Proficiency of Cambridge, Proficiency of Michigan
Italian: Diploma Medio Palso
Computers: Microsoft Office, use of Bioinformatic programs and databases
Medical Service:
25/11/2010 - 25/11/2011: Military service in Greek Navy as a General Practitioner
24/4/2012 - 23/4/2013: Rural doctor in Amaliada General Hospital, Simopoulo Health Center, Medical office of Lampeia
24/4/2013 - 25/12/2015: Registrar in Internal Medicine, Department of Internal Medicine, “A. Fleming” General Hospital, Melissia, Athens
2/11/2016 - 1/11/2019: Registrar in Medical Oncology, Department of Clinical Therapeutics, General Hospital Alexandra
1/04/2019 - 1/11/2019: Clinical rotation to General Oncology Department, UZ Leuven, Belgium
Continuous Medical Education
2013 January: ACLS course
2017 October: GCP training completion
Publications:
1. Liontos M, Sotiropoulou M, Kaparelou M, Tzannis K, Tsironis G, Kyriazoglou A, Tsiara A, Zakopoulou R, Koutsoukos K, Zagouri F, Thomakos N, Haidopoulos D, Rodolakis A, Dimopoulos MA, Bamias A. Lymphocytic infiltration and Chemotherapy Response Score as prognostic markers in ovarian cancer patients treated with Neoadjuvant chemotherapy.Gynecol Oncol. 2020 Mar 12. pii: S0090-8258(20)30224-9. doi: 10.1016/j.ygyno.2020.03.008. [Epub ahead of print]
2. Kyriazoglou A, Koutsoukos K, Zagouri F, Liontos M, Dimitriadis E, Tiniakos D, Dimopoulos MA. Metastatic Hepatic Epithelioid Hemangioendothelioma Treated with Olaratumab: A Falling Star Rising? Ther Clin Risk Manag. 2020 Feb 27;16:141-146. doi: 10.2147/TCRM.S220804. eCollection 2020
3. Eleni Zografos, Flora Zagouri, Despoina Kalapanida, Roubini Zakopoulou, Anastasios Kyriazoglou, Kleoniki Apostolidou, Maria Gazouli, Meletios-Athanasios Dimopoulos Prognostic role of microRNAs in Breast cancer: a
systematic review, Oncotarget, PMID: 31903173, PMCID: PMC6935258, DOI: 10.18632/oncotarget.27327
4. Kyriazoglou A, et al. Emerging Insights Into the Role of the Hippo Pathway in Multiple Myeloma and Associated Bone Disease, Clin Lymphoma Myeloma Leuk 2019. PMID 31734019
5. Zagouri F, Korakiti AM, Zakopoulou R, Kyriazoglou A, Zografos E, Haidopoulos D, Apostolidou K, Papatheodoridi MA, Dimopoulos MA. Taxanes during pregnancy in cervical cancer: A systematic review and pooled analysis. Cancer Treat Rev. 2019 Aug 6;79:101885. doi: 10.1016/j.ctrv.2019.08.001. [Epub ahead of print] Review.PMID: 31442939
6. Anastasios Kyriazoglou, Flora Zagouri, Meletios Athanasios Dimopoulos Olaratumab administered in two cases of phyllodes tumor of the breast: end of the beginning? ESMO OPEN, 2019 Jun 25;4(3):e000479. doi: 10.1136/esmoopen-2018-000479. eCollection 2019
7. Wen-Bin Ou, Nan Ni, Rui Zuo, Weihao Zhuang, Meijun Zhu, Anastasios Kyriazoglou, Duolin Wu, Grant Eilers, George Demetri, Hai-Bo Qiu, Bin Li, Adrian Marino-Enriquez, and Jonathan Fletcher . Cyclin D1 is a Mediator of Gastrointestinal Stromal Tumor KIT-independence, Oncogene, 2019 Aug 1. doi: 10.1038/s41388-019-0894-3
8. A.Kyriazoglou, G.Tsironis, M.Liontos, A.Papakosta, L.Mahaira, N.Thomakos, G.Morphopoulos, I.Papaspyrou, A.Bamias Ewing’s sarcoma of the cervix: a case report of an unusual diagnosis in pregnancy treated with surgery, adjuvant VIDE and Radiotherapy, Oncology Letters, 2019 Jun;17(6):5529-5535. doi: 10.3892/ol.2019.10267. Epub 2019 Apr 18
9. Liontos M, Kyriazoglou A, Dimitriadis I, Dimopoulos MA, Bamias A. Systemic therapy in cervical cancer: 30 years in review. Crit Rev Oncol Hematol. 2019 May;137:9-17. doi: 10.1016/j.critrevonc.2019.02.009. Epub 2019 Feb 28. Review. PMID: 31014518
10. Kyriazoglou A, Zagouri F, Fotiou D, Dimitrakakis C, Marinopoulos S, Zakopoulou R, Kaparelou M, Zygogianni A, Dimopoulos MA. Discrepancies of current recommendations in breast cancer follow-up: a systematic review. Breast Cancer. 2019 Mar 18. doi: 10.1007/s12282-019-00963-6. [Epub ahead of print]PMID: 30887287
11. Kyriazoglou A, Liontos M, Ziogas DC, Zagouri F, Koutsoukos K, Tsironis G, Tsiara A, Kaparelou M, Zakopoulou R, Thomakos N, Haidopoulos D, Papaspyrou I, Rodolakis A, Bamias A, Dimopoulos MA. Management of uterine sarcomas and prognostic indicators: real world data from a single-institution. BMC Cancer. 2018 Dec 13;18(1):1247. doi: 10.1186/s12885-018-5156-1. PMID: 30541504 Free PMC Article
12. Kyriazoglou A, Liontos M, Papadopoulos C, Bilali A, Kostouros E, Pagoni S, Doumas K, Dimopoulos MA, Bamias A. Guillain-Barré Syndrome Related to Nivolumab: Case Report of a Patient With Urothelial Cancer and Review of the Literature. Clin Genitourin Cancer. 2018 Dec 4. pii: S1558-
7673(18)30781-X. doi: 10.1016/j.clgc.2018.11.022. [Epub ahead of print] No abstract available. PMID: 30612920
13. Tsironis G, Ziogas DC, Kyriazoglou A, Lykka M, Koutsoukos K, Bamias A, Dimopoulos MA. Breakthroughs in the treatment of advanced squamous-cell NSCLC: not the neglected sibling anymore? Ann Transl Med. 2018 Apr;6(8):143. doi: 10.21037/atm.2018.02.18. Review.
14. A. Kyriazoglou1 ,G.Rigakos1, A. Vernadou, S. Papadopoulos, E. Skarpidi, P.Nomikos, C. Dardoufas, G.Nassioulas, G. Kouvatseas, O. Spyri, S. Labropoulos, E.Razis. Bevacizumab in high grade glioma: is there a subgroup that benefits? DOI: 10.15761/HMO.1000131, Hematology and Medical Oncology, June 15, 2017
15. Dimitrios C. Ziogas, Michalis Liontos, Anastasios Kyriazoglou, Georgios Tsironis, Aristotelis Bamias & Meletios-Athanasios Dimopoulos Gefitinib: an “orphan” drug for non-small cell lung cancer Pages 899-906 | Received 07 Jun 2017, Accepted 12 Oct 2017, Accepted author version posted online: 13 Oct 2017, Published online: 17 Oct 2017
16. Anastasios Kyriazoglou, Ioannis Dimitriadis, Aristotelis Bamias Developing an algorithm for the management of Renal Cell Carcinoma: focus on metastatic disease, Published Online: 2017-06-30 | DOI: https://doi.org/10.1515/fco-2015-0025
17. Kyriazoglou A, Christopoulos C. Severe dental erosion associated with imatinib mesylate therapy. Acta Oncol. 2014 Jan 21. (doi:10.3109/0284186X.2013.879999)
18. Kyriazoglou AI, Rizou H, Dimitriadis E, Arnogiannaki N, Agnantis N, Pandis N. Cytogenetic analysis of a low-grade secondary peripheral chondrosarcoma arising in synovial chondromatosis. In Vivo. 2013 Jan-Feb;27(1):57-60.
19. Kyriazoglou AI, Vieira J, Dimitriadis E, Arnogiannaki N, Teixeira MR, Pandis N. 12q amplification defines a subtype of extraskeletal osteosarcoma with good prognosis that is the soft tissue homologue of parosteal osteosarcoma. Cancer Genet. 2012 Jun;205(6):332-6.
20. Kyriazoglou AI, Dimitriadis E, Arnogiannaki N, Brandal P, Heim S, Pandis N. Similar cytogenetic findings in two synchronous secondary peripheral chondrosarcomas in a patient with multiple osteochondromas. Cancer Genet. 2011 Dec;204(12):677-81.
21. Dimitriadis E, Rontogianni D, Kyriazoglou A, Takou A, Frangia K, Pandis N, Trangas T, Novel SYT-SSX fusion transcript variants in synovial sarcoma. Cancer Genet Cytogenet. 2009 Nov;195(1):54-8.
22. Tsarouha H, Kyriazoglou AI, Ribeiro FR, Teixeira MR, Agnantis N, Pandis N. Chromosome analysis and molecular cytogenetic investigations of an epithelioid hemangioendothelioma, Cancer Genet Cytogenet 2006 Sep;169(2):164-8
Fellowships:
2015 - 2016: Postdoctoral Research Fellowship from HESMO (Hellenic Society of Medical Oncology) for Brigham and Women’s Hospital, an affiliate of Harvard Medical School, Boston, MA USA
2018: Research fellowship support from HESMO for the study: «Genetic analysis of DNA double strand break repair pathways in sarcomas»
2019: Research fellowship support from HESMO for the study: «Hippo pathway in pregnancy related breast cancer»
2019: Fellowship from HESMO (Hellenic Society of Medical Oncology) for clinical rotation to General Oncology Department, UZ Leuven, Belgium
2020: Fellowship Sarc-DPT from GSRT (General Secretary of Research and Technology) program «ΕΠΙΧΕΙΡΩ-ΡΕΥΝΩ-ΚΑΙΝΟΤΟΜΩ», in collaboration with EKETA, Hellenic group of sarcomas and rare tumors, Department of Clinical Therapeutics, ΒΑΡΕΛΑΣ Α.Ε., BioOncology Care and Healthink.
Clinical trials participation:
- JPCF MonarchE trial, Lilly
- CA209-9ER, BMS
- Athena (CO-338-087), Clovis Oncology
- 13Y-MC-JPBZ MonarcHER trial, Lilly
- EPOCA study, Qualitis
- CABO-GIST, EORTC 1317
- WO39613, Covance, Roche
- CA2098MX, BMS
Presentations at Scientific Conferences:
2006: The practical applications of Genetics and Molecular Biology methods in the diagnosis and treatment of myoskeletal tumors, 10th Panhellenic Congress of Orthopaedic Oncology, Kalamata, 5-6 May 2006
2009: Multi-color banding studies of a low grade chondrosarcoma arising in synovial chondromatosis, 3rd Hellenic-Jordanian Congress of Pathology, 29-31 October, Limassol, Cyprus
2013: Genetics and molecular cytogenetics on the diagnosis of sarcomas, 69th Panhellenic Congress of Orthopaedics and Traumatology, 2-5 October, Athens, Greece, oral presentation
2017: Biomarkers: the development, Congress: «From Chemotherapy to Molecular targeting», 8-10 December 2017, Divani Caravel, Athens
2017: Young MMOF- Mentorship session, Gynecological cancer Case presentation, 5th Congress of the Mediterranean multidisciplinary oncology forum, 23-25 November, Hilton, Athens, Greece
2018: Evaluation of Chemotherapy Response Score and lymphocytic infiltration as prognostic markers in ovarian cancer patients treated with Neoadjuvant chemotherapy, ESMO 2018 Congress Munich, Germany, poster presentation
2019: Endometrial stromal sarcomas a review, Second Masterclass of sarcomas, Greek Group of sarcomas and rare tumors, Athens, Greece 15-16 March 2019, oral presentation
2019: Clinical case presentation: young male with retroperitoneal leiomyosarcoma, 13th Educational Seminar of Molecular Oncology and targeted therapy, 29-31 March, Ioannina, Greece, oral presentation
2019: Study of efficacy and safety of Axitinib beyond the second line in patients with metastatic renal cell carcinoma, Greek Congress of Clinical Oncology, 18-21 April 2019, Athens, Greece, poster presentation
2019: Expression analysis of NHEJ and HR genes in Ewing sarcomas: indications of DSB repair dysfunction, A.Kyriazoglou et al., ESMO 2019, Barcelona, Spain 27 September- 1 Ovtober 2019, poster session
2019: BCOR sarcomas: a case series with a new splice variant of BCOR/CCNB3 fusion gene. A.Kyriazoglou et al., CTOS 2019, Tokyo, Japan, 13-16 November 2019, poster session
2020: Nephrectomy and metastasectomy in mRCC patient in the era of Immunotherapy and Targeted therapies, Thessaloniki, 6-7 March 2020, Modern Oncology, oral presentation
Participation in international Workshops:
2006: 10th European Workshop of Molecular Cytogenetics in Human Solid Tumors, La Grande Motte, France, 8 - 11 June 2006
2007: Training Workshop on mFISH and mBAND at Metasystems, Altlusheim, Germany, 12 - 14 September 2007
2008: 11th European Workshop of Molecular Cytogenetics in Human Solid Tumors, Bilbao , 6 - 9 September 2008
2014: 23rd AACR Workshop of Molecular Biology in Clinical Oncology, Snowmass Village, Colorando, July 20 - 26, 2014
2018: ESMO Preceptorship on Metastatic Bladder and Kidney Cancer - Zurich - 23-24 Nov 2018
Lab experience:
October 2003 - June 2004: Diploma thesis: “Cytogenetic analyses of mesenchymal tumors” Department of Genetics, Saint Savas Hospital Supervisor: Dr Nikos Pandis
January 2005 - December 2009: PhD thesis: “Genetic analyses and clinicopathological correlations of mesenchymal tumors” Department of Genetics, Saint Savas Hospital Supervisor: Dr Nikos Pandis
January 2016 - September 2016: Postdoctoral Research: Endometrial stromal sarcomas (ESS) with YFAM fusion protein and Hippo pathway Department of Pathology, Brigham and Women’s Hospital (BWH), Harvard Medical School, Boston, USA Supervisor: Professor Jonathan Fletcher
Teaching experience:
2005 - 2010: teaching Biology in AEIdromon and Drakos Educational Organisation
2010 - today: teaching in AKTIS panepistimiakon Educational Organisation (Biology, Genetics, Physiology, Biochemistry, Clinical Chemistry, Internal Medicine, Anatomy, Histology)
2011 - 2012: teaching in IEK IPPOKRATEIOS (anatomy, orthopaedics, rheumatology, first aids, neurology, microbiology, physiology)
2018: Presentation at the MBA of Surgical Oncology, Medical School of Athens, University of Athens, “Breast cancer and pregnancy”, 18/5/2018
2020: Presentation at the MBA of Surgical Oncology, Medical School of Athens, University of Athens, “Cancer and pregnancy”, 9/5/2020
Memberships:
Member of the Hellenic Society of Medical Oncology (HESMO)
Member of the Young Greek Oncologists Group (HEGYO)
Member of the Greek Group of Sarcomas and rare tumors
Member of Panhellenic Society of Bioscientists
